Which action is part of Buddy Aid for nerve agent poisoning?

• A. Administering ATANA only
• B. Administering CANA only
• C. Administering both ATANA and CANA
• D. Administering no antidote

Answer: (C)

Nerve agent poisoning requires two antidotes that work in complementary ways: one to block the effects of acetylcholine at muscarinic receptors, and the other to reactivate the enzyme that breaks down acetylcholine. Administering ATANA provides the atropine-like effect to reduce secretions, bronchoconstriction, and bradycardia, while CANA delivers the agent that reactivates acetylcholinesterase, addressing the underlying enzyme inhibition and reducing overall cholinergic burden. Giving both antidotes in Buddy Aid ensures immediate relief of dangerous symptoms and tackles the root cause of the toxicity, rather than delaying one component or relying on only one mechanism. If only one were given, significant symptoms could persist or worsen. Therefore, administering both ATANA and CANA is the best immediate action when available, followed by rapid medical care and decontamination.